The known protein universe just got a lot bigger. A newly released artificial-intelligence tool has generated an atlas of more than one billion predicted protein structures and billions more protein ...

Proteins are the molecular workhorses of cells. To understand their functions, scientists soon realized that they had to figure out proteins’ shapes. But solving a protein structure is a challenging ...

In the wee hours of an October morning, David Baker, a protein biologist at the University of Washington (UW), received the most-awaited phone call in a scientist’s career. Halfway around the world, ...

Efforts to unlock the mysteries of proteins, building blocks of life, have earned three scientists the 2024 Nobel Prize in chemistry. The prize goes to David Baker “for computational protein design,” ...

H5_fold-0_Chantal, H5_fold-0_Elsa, H6_fold-C_Rei, H6_fold-Z_Gogy, H6_fold-U_Nomur, and H7_fold-K_Mussoc are presented. For each de novo designed protein, the computational model is shown on the left, ...

The tiny protein known as transthyretin can cause big problems in the body when it misfolds after secretion. While healthy transthyretin moves hormones through blood and spinal fluid, misfolded ...

A South Korean research team has successfully designed large protein structures that replicate the natural assembly principles of viruses in nature by collaborating with a Nobel laureate and utilizing ...