Medscape

APAF-CRT: 'Ablate and Pace' Cuts Mortality in Narrow-QRS HF, Permanent AF

In the APAF-CRT trial, mortality fell more than 70% over 4 years for such patients with HF and narrow QRS intervals who were assigned to ablate-and-pace — that is, CRT after creation of heart block by ...
Nature

Variants in Apaf-1 segregating with major depression promote apoptosome function

It was necessary to amplify the gene in two pieces (using primers A1+A2, and A3+A4), which were subsequently ligated using the internal EcoRI site at base 2630 in NM_181861. The resultant APAF1 was ...
Medscape

APAF-CRT: 'Ablate and Pace' for Permanent AF With Heart Failure, Narrow QRS

MUNICH — Patients with heart failure (HF) and narrow electrocardiographic QRS intervals aren't considered appropriate for cardiac resynchronization therapy (CRT), but evidence is growing that CRT may ...
ascopubs.org

Loss of Apaf-1 expression and resistance to hypoxia-induced apoptosis in cervical cancer

Serum YKL-40 levels in patients with cervical cancer are elevated compared to patients with cervical intraepithelial neoplasia and healthy controls No significant financial relationships to disclose.