Protein sorting in the secretory pathway is essential for cellular compartmentalization and homeostasis in eukaryotic cells. The endoplasmic reticulum (ER) is the biosynthetic and folding factory of ...
Glycosylphosphatidylinositol (GPI)-anchored proteins are attached to the lumenal side of membranes of the secretory and endocytic pathways by a glycolipid anchor. As they are not exposed to the ...