Neutrophils constitute the main infiltrating cell type in Behçet’s syndrome lesions. By producing excessive levels of reactive oxygen species and releasing neutrophil extracellular traps, neutrophils ...

Evidence suggests a greater prevalence of fibromyalgia among people with Behçet's disease than in the general population. Just as fibromyalgia appears to be more prevalent among women than men in the ...

Oral ulcers, the hallmark of Behçet’s syndrome, can be resistant to conventional treatment; therefore, alternative agents are needed. Apremilast is an oral phosphodiesterase-4 inhibitor that modulates ...

The monoclonal antibody ustekinumab (Stelara), which targets interleukin (IL)-12 and IL-23, appeared to be effective for clearing oral ulcers in Behcet's disease in a multicenter open-label study ...

What Is Behcet’s Syndrome? Behcet’s syndrome (also called Behcet’s disease) is rare condition that causes your body’s blood vessels to swell. This can cause symptoms throughout your body. Sores inside ...

Desbois and colleagues evaluated factors associated with relapse of thrombosis and mortality in patients with Behçet disease by performing chart reviews of 807 patients, 296 (37%) of whom had a total ...

Please provide your email address to receive an email when new articles are posted on . Patients with vascular manifestations of Behçet’s disease who received treatment with anticoagulants did not ...

Please provide your email address to receive an email when new articles are posted on . The rare and complex Behcet’s disease is often misdiagnosed or undiagnosed, leading to significant, but ...

SAN DIEGO — Apremilast quickly relieves painful oral and genital ulcers in patients with Behçet's disease and improves quality of life, compared with placebo, results of a phase 2 study suggest. "The ...

The Food and Drug Administration (FDA) has approved Otezla (apremilast; Celgene) for the treatment of adult patients with oral ulcers associated with Behçet’s disease. The approval was based on data ...