Industry is adapting to the increasing complexity and poor solubility and bioavailability of molecules in the pipeline. Poor solubility and low bioavailability have hindered the development pipeline ...
When it comes to supplements, absorption matters just as much as the dosage. You could be taking the most potent multivitamin or mineral supplement, but if your body can’t absorb it properly, it won’t ...
I drink a full glass of milk every day and eat cheese, but still, I am deficient in calcium. I include iron-rich foods in my diet to meet my daily requirement of iron, but I am still anemic. It is ...
The field of functional foods plays a critical role in advancing sustainable nutrition and human health. Phytochemicals - bioactive compounds found in ...
Want to improve the nutritional benefits of your favourite foods? You may need to start thinking about bioavailability… We all want to get the most out of the food we eat, but there’s much more to ...
Limited-sampling models for irinotecan pharmacokinetics-pharmacodynamics: prediction of biliary index and intestinal toxicity. Twenty-nine patients received oral EP (capsules, 50 to 150 mg/m2/d of E ...
The randomized, open-label, crossover clinical study, led by Priyank Rathi, MD, was published in the science journal Phytomedicine Plus, last July. It evaluated the bioavailability in 16 healthy human ...
Upon ingestion, the new Enzian dosage form resides in the stomach for several hours and steadily delivers drug into the blood. This enables enhanced effectiveness of many life-saving drug therapies.
Marketed formulations of extended phenytoin sodium -- long a difficult medication to titrate because of its unique absorption and saturable elimination pharmacokinetics -- may not be bioequivalent, ...
Although efforts have been made to improve solubility, many poorly soluble drugs still reach the market. Peter Nielsen discusses new developments in solubilisation technology, which could help those ...
Negativity around processed foods does not tell the whole story according to a new paper published by the Institute of Food Technologists Processed food, especially ultra-processed foods (UPF) is, for ...