The molecule called CD44 is a transmembrane glycoprotein involved in cell to cell adhesion, interactions, and signaling. It is also a receptor of hyaluronic acid (HA) which is mechanistically involved ...
One of the main obstacles to successfully treating breast cancer is the cells' ability to change in ways that make them resistant to treatment. Understanding the cellular mechanisms that mediate this ...
Protein biosignature identified by LC-MS/MS in classifying breast cancer and predicting tumor response to neoadjuvant therapy. Methods: Histological analysis of the breast was carried out on mounted ...
Researchers investigating the role of the protein CD44 in obesity and metabolic health found that CD44-deficient mice stayed lean even on a high-fat diet, while the control mice developed obesity. A ...
Uniform approach to risk classification and treatment assignment for children with acute lymphoblastic leukemia. Adjuvant cyclophosphamide, methotrexate, and fluorouracil versus fluorouracil, ...
The image shows prostate cancer cells in which KLF4 (red) and the CD44 protein (green) on the cell membrane are stained. There is a challenge related to prostate and many other cancers that cancer ...
Researchers have found a marker on head and neck tumor cells that indicates which cells are capable of fueling the cancer's growth. The finding is the first evidence of cancer stem cells in head and ...
A group of researchers from the University of Seville and the Seville Biomedicine Institute (Instituto de Biomedicina de Sevilla - IBiS) has published a study in which they determine that a protein ...
A study in The American Journal of Pathology found that mice with a CD44 protein deficiency remain slim, despite being on a high-fat diet. The image depicts the working model for the study. The ...
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