A test measuring proteins in spinal fluid may help support the diagnosis of MS, especially in patients whose disease is harder to diagnose.

Impact of Broadening Trial Eligibility Criteria on the Inclusion of Patients With Brain Metastases in Cancer Clinical Trials: Time Series Analyses for 2012-2022 Effective diagnosis, prognostication, ...

The cannulation of the cisterna magna in the rat is a valuable model for in-vivo sampling of cerebrospinal fluid for studying delivery of new drugs into the central nervous system or disease models.

Cerebrospinal fluid (CSF) is a type of clear liquid that surrounds, protects, and cushions your brain and spinal cord from possible injuries. The fluid is held in place by the dura mater, a dense ...

Common symptoms of a spinal fluid leak are head pain, nausea, and neck stiffness. The outlook for someone with a spinal fluid leak is typically good. It often heals itself with no long-term ...

More than 20 y ago, we developed an animal model for chronic and continuous collection of cerebrospinal fluid (CSF) from conscious rhesus macaques. Since our previous publication in 2003, we have ...

Twenty-four of 25 patients with bacterial meningitis and nine of 11 with CNS viral infection had increased LDH activity in the CSF. The mean levels were 112.8 units per milliliter in bacterial, 193 ...

For a human, one of the first signs someone is getting old is the inability to remember little things; maybe they misplace their keys, or get lost on an oft-taken route. For a laboratory mouse, it’s ...