Researchers at the Cancer Research Institute and the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, have ...

The central image depicts currently used strategies for clinical targeting of TGF-β. Below are methods applicable from preclinical screening to clinical practice, including using humanized mouse ...

Researchers at the Cancer Research Institute and the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, have uncovered a critical mechanism that enables gastric cancer to spread to ...

Colorectal cancer is the third most common cancer in the United States. Although screening has led to a decrease in incidence over the past 20 years, early-onset colorectal cancer has been rising.

CD25 expression has long been recognized as an adverse prognostic marker in acute leukemias including acute myeloid leukemia ...

Innate immune sensors – known as pattern recognition receptors (PRRs) – detect specific molecular components of bacterial or ...

The researchers used lipid nanoparticles (LNPs) to deliver cyclic GMP-AMP (cGAMP) synthase (cGAS) mRNA to cancer cells. This results in production of the endogenous stimulator of interferon genes ...

Inflammatory bowel disease, often called IBD, is a long-term condition that causes ongoing inflammation in the digestive system. The two main types are Crohn’s disease and ulcerative colitis. People ...

As multi-cancer early detection (MCED) testing gains momentum, experts are honing their focus on what comes next for patients with a positive MCED test result. Understanding the diagnostic pathways ...

Colorectal tumors that underwent somatic next-generation sequencing (NGS) for 154-168 genes in an in-house laboratory between 2015 and 2022 were retrospectively identified. Microsatellite instability ...