mRNAs are protected at their 5′ ends by a cap structure consisting of an N7-methylated GTP molecule linked to the first transcribed nucleotide by a 5′–5′ triphosphate bond. The cap structure is ...
mRNA vaccines and therapeutics are rapidly growing, driven by the success of COVID-19 vaccines. The 5’ cap structure is crucial for mRNA stability and expression. However, in-vitro transcribed mRNA ...
A study of an enzyme used by cells to care for the ends of their chromosomes may offer scientists new avenues for intervening in cancer and aging. Researchers in the lab of Princeton biologist ...
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