Cells in the human body accumulate cancer-promoting mutations throughout their lifespan, yet these mutations rarely drive tumour formation. Tumours in a given tissue usually originate from a specific ...

By simulating the life cycle of a minimal bacterial cell—from DNA replication to protein translation to metabolism and cell ...

The awe-inspiring process of cell division can turn a fertilized egg into a baby – or a cancerous cell into a malignant tumor. With so much at stake, nature keeps it tightly controlled in a process ...

Caulobacter crescentus has emerged as a premier model for studying bacterial cell cycle regulation due to its distinctive asymmetric division, which produces two morphologically and functionally ...

A metabolic enzyme studied for over seven decades has a hidden second function—it can unwind RNA and promote cell cycle progression, an additional function beyond its role in energy production, ...

Every day, our bodies perform around 330 billion cell divisions to keep us alive and functioning. These divisions rely on the cell cycle, which has been in place since the earliest bacteria. The ...

Inside the human airway, a certain cell type reigns supreme: multiciliated cells, decorated with dozens of hair-like cilia all beating in tandem. These cells are responsible for clearing out foreign ...

“We closed a gap in our knowledge that was open for 10 years,” says Duccio Conti, a postdoc in the Musacchio group and first author of the publication. In healthy DNA replication, at first, each new ...