Myc is a highly unstable transcription factor that is destroyed by ubiquitin (Ub)-mediated proteolysis. We have previously identified an amino-terminal ‘degron’ within Myc that signals its destruction ...
Hematopoietic stem cells can replenish all the different cell types of our blood system. For this reason, hematopoietic stem cells are the cells used in many blood diseases when patients need ...
Ancient embedded elements in our DNA from generations past can activate a powerful immune response to kill cancer cells like an infection. The work builds on Princess Margaret Cancer Centre Senior ...
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