A new study challenges the century-old dominance of Mendelian genetics, arguing that most traits arise from complex networks of thousands of genes rather than single-gene inheritance. Researchers ...

A single-cell platform reveals that many genetic mutations converge on shared cellular programs, pointing to simpler, more ...

Individuals that share the same deletion of a portion of chromosome 16 are at risk of developing neurodevelopmental disorders ...

Deep learning models have shown great potential in predicting and engineering functional enzymes and proteins. Does this prowess extend to other fields of biology as well? Contrary to expectations, a ...

Recent studies are challenging the long-dominant Mendelian view of inheritance, highlighting the need to incorporate polygenic and quantitative models into genetics research and education. Evidence ...

Genome assemblies from 65 individuals, representing a variety of the world’s populations, are advancing the scientific exploration of complex genetic structural variation. Structural variations are ...

In people with type 1 diabetes (T1D), the immune system shuts down the body's ability to make the hormone insulin, ...

The Collaborative Cross (CC) mouse resource has emerged as an indispensable platform for elucidating the genetic basis of complex traits. By combining high levels of genetic diversity from eight ...

Improving the genetic circuits in eukaryotic protein production systems—like human cell lines or Chinese hamster ovaries—has the potential to enhance their value so they may offer not only their own ...

It’s estimated that one in four adults will suffer from some type of anxiety disorder at some point, such as phobias of specific things; generalized anxiety that affects people over a long period of ...

Researchers have uncovered the origins and genetic diversity of the Fulani, one of Africa's largest pastoral populations. The study reveals a complex genetic ancestry with influences from both North ...