The Collaborative Cross (CC) mouse resource has emerged as an indispensable platform for elucidating the genetic basis of complex traits. By combining high levels of genetic diversity from eight ...

Scientists have identified how specific genetic changes function in cells to influence disease risk and other human health traits. By probing regions of DNA previously linked to disease, the work has ...

A study by researchers at The Jackson Laboratory (JAX), the Broad Institute, and Yale University has identified how specific genetic changes function in cells to influence disease risk and other human ...

Today's biomedical researchers are relentlessly searching for genes that drive disease, with the goal of creating therapies that target those genes to restore health. When a single gene is the culprit ...

Northwestern University biophysicists have developed a new computational tool for identifying the gene combinations underlying complex illnesses like diabetes, cancer and asthma. Unlike single-gene ...

Sequencing nearly half a million genomes, researchers show that most additive genetic influences on height, lipids, and other complex traits are now directly measurable, while pinpointing ultra-rare ...

Putting the two sources together allowed the researchers to build a detailed map of the gene networks that influence red blood cell traits. The picture that emerged showed a remarkably complex genetic ...

DALLAS--(BUSINESS WIRE)--In an extraordinary achievement of advanced multiplexed genome engineering, Colossal Biosciences announces the birth of the Colossal Woolly Mouse—mice engineered to express ...

Streptococcus Pyogenes (Group A Strep). Credit - NIAID, CC SA 2.0. Streptococcus Pyogenes (Group A Strep). Credit - NIAID, CC SA 2.0. A new tool could pave the way for new multi-target therapies, ...