Researchers in China have developed a new method that allows them to insert long stretches of DNA into a genome. The process, named GRAND editing, is one of a handful of new systems aimed at using two ...

Researchers from Tokyo Medical and Dental University (TMDU) and Ionis Pharmaceuticals, USA, report a modification wherein replacing the RNA strand of a heteroduplex oligonucleotide with DNA may ...

The world’s most famous molecule – the DNA double helix – sometimes doubles up again. Researchers have now found this quadruple-stranded form in healthy human cells for the first time. Four-stranded ...

Antisense oligonucleotides (ASOs) are small, single-stranded molecules that can suppress the expression of targeted genes and thereby achieve therapeutic effects. However, many ASO-based drug ...

Using an atomic force microscope tip as a pen and different single-stranded DNA as inks, scientists at Northwestern University have demonstrated a technique that could lead to the ultimate ...

DNA, or deoxyribonucleic acid, is the hereditary material found in nearly all living organisms. It carries the genetic instructions for the development, functioning, growth, and reproduction of all ...

CRISPR-Cas9 has been editing the human genome for the past decade. Although the types of edits have varied, an unsolved challenge has been the integration of large pieces of DNA without ...