The alternative text for this image may have been generated using AI. In this Progress article, we discuss recent findings that highlight the significance of eukaryotic DNA topoisomerases in ...

Transcription is the process by which DNA is converted into messenger RNA in preparation for translation into a functional product. Extrinsic agents, such as ionizing radiation or chemical mutagen and ...

A team of researchers has found that transcription factors have a tendency to bind strongly to 'mismatched' sections of DNA, i.e. sections of the genome that were not copied correctly. The strong ...

RNA polymerase, the enzyme that synthesizes RNA from DNA during transcription, has been captured mid-reaction for the first ...

The accuracy of transcription processes varies widely among species, across cell types and within distinct regions of the genome, with profound consequences for health and disease.DNA transcription is ...

Scientists had previously assumed that gene activity is controlled by the binding strength and the proximity of the binding site to the gene. Researchers have now discovered that the DNA segment to ...