Scientists at the University of North Carolina (UNC) at Chapel Hill have resolved the structure of the D 2 dopamine receptor (DRD2) bound to the antipsychotic drug risperidone. The researchers, led by ...
Prasad, K. M., Talkowski, M. E., Chowdari, K. V., McClain, L., Yolken, R. H. & Nimgaonkar, V. L. Candidate genes and their interactions with other genetic ...
The neurotransmitter dopamine is believed to influence the development and/or maintenance of alcoholism. Findings regarding the dopamine D2 receptor gene, however, have been inconsistent. New research ...
A phase 1b/2 study of the combination of the IDO pathway inhibitor indoximod and temozolomide for adult patients with temozolomide-refractory primary malignant brain tumors: Safety analysis and ...
Two years ago at a scientific meeting, Bryan L. Roth of the University of North Carolina, Chapel Hill, announced that he and his colleagues were trying to solve the structure of the D 2 dopamine ...
Although antipsychotic drugs are among the most widely prescribed medications, individuals with schizophrenia, bipolar disorder and autism-spectrum disorders often experience severe side effects ...
Pharmacogenomics. 2014;15(9):1253-1271. DRD3 is mapped at chromosome 3q13 and encodes dopamine receptor D3. Numerous studies were reported with this gene, mainly with the functional polymorphism ...
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