CYP3A-inducing antiepileptics decrease sorafenib exposures: Results of a phase II study in adults with recurrent glioblastoma. Background: The apparent diffusion coefficient (ADC) obtained from ...

For therapeutic biomolecules stability is a key quality attribute that is important for establishing drug-like properties and applicability for use in humans. However, it is both time-intensive and ...

Characterization of net charge as well as the overall non-specific self-interactions of biotherapeutics proteins is essential in assessing their aggregation propensity. These colloidal stability ...