T cell activation—the process by which these key immune defenders recognize threats and mobilize against them—depends on exquisitely timed molecular signals. Now researchers have captured one of the ...

We owe a lot to tissue resident memory T cells (T RM). These specialized immune cells are among the body's first responders to disease. Rather than coursing through the bloodstream-as many T cells ...

For decades, scientists understood inducible nitric oxide synthase, or iNOS, as a one-trick enzyme. Its job was to churn out nitric oxide, a reactive molecule the immune system uses to kill bacteria ...

A new study shows how an anticancer drug triggers an 'outside in' signal that gets it sucked into a cancer cell. The work reveals a new signaling mechanism that could be exploited for delivering other ...

Researchers from Queen Mary University of London have uncovered a previously unknown mechanism by which HIV-1 can infect ...

A fruit fly eats a meal laced with harmful bacteria, gets sick, and never touches that food again. That much scientists already knew. What they did not know was how the fly’s body taught its brain to ...

The thymus is essential for producing the T cells that protect us from infections and cancer. But this organ is also highly sensitive to damage. Treatments like chemotherapy, radiation, and ...