Researchers report that they are at the forefront of discovering and mapping out the complexities of the structures involved in a process of pri-miRNA biogenesis. For the first time, the team has ...

Each cell of our body is the result of an orchestra of sophisticated mechanisms that control which genes are and are not expressed at any given time. Partly, this is possible thanks to the ...

The RNA endonuclease Drosha is required for myelopoiesis by its direct cleavage of stem-loop structures in mRNAs encoding Myl9 and Todr1. miRNAs are small RNAs of approximately 22 nucleotides that ...

Messenger RNA (mRNA) levels of the RNase III enzymes, Dicer and Drosha, are associated with clinical outcomes in patients with ovarian cancer, according to US researchers. High expression of both of ...

Results published in NEJM links high levels of both to a median survival of 11 years and lower levels to 2.66 years. The level of Dicer and Drosha proteins in a woman’s ovarian cancer are strongly ...

To date, it has been assumed that the differentiation of stem cells depends on the environment they are embedded in. A research group at the University of Basel now describes for the first time a ...

TDP-43 shepherds select microRNAs through their maturation process from nuclear transcripts to grown-up regulatory fragments set loose in the cytoplasm, according to a paper in the February 9 ...

video: Scientists working at the IBS Center for RNA Research in South Korea are at the forefront of discovering and mapping out the complexities of the structures involved in this process of pri-miRNA ...

Each cell of our body is the result of an orchestra of sophisticated mechanisms that control which genes are and are not expressed at any given time. Partly, this is possible thanks to the ...