Remarkable scientific progress over the past five decades has helped us develop knowledge of how drugs of abuse induce pleasure, reinforce use, and lead to the compulsive self-administration we call ...

Nick Padlo’s addiction to alcohol and drugs didn’t happen overnight. “I was using them as a tool to cope with depression and anxiety,” says the recovered addict and founder of Sophros Recovery in ...

The popular class of weight loss drugs known as GLP-1s have shown to be effective in curbing cravings beyond food. A few early studies have suggested that GLP-1 medications can do a lot to alleviate ...

Al-Aly is a physician and researcher at Washington University in St. Louis and chief of research at the VA Saint Louis Health Care System. At a dinner party recently, someone poured my friend a glass ...

GLP-1 drugs, originally developed for diabetes and obesity, may also curb addictive behaviors by acting on reward circuits in the brain. Early trials show reductions in alcohol intake, opioid seeking, ...

Athletes, actors, politicians, and others often develop substance abuse disorders and some die from drug-related deaths. At the same time, their life history, drug use, and risk-taking shows the rest ...

A patient of mine, a veteran who had tried to quit smoking for over a decade, told me that after he started a GLP-1 drug for his diabetes, he lost interest in cigarettes. He didn’t use a patch. He ...