New technology enables the insertion of a large segment of DNA into a genome, potentially expanding gene therapy treatment ...

Scientists at The University of Texas at Austin have developed a revolutionary gene-editing method using bacterial retrons that can correct multiple disease-causing mutations at once. Unlike ...

In a recent study published in the Microorganisms journal, researchers in China reviewed the uses of bacterial-artificial-chromosome (BAC)-based genome editing techniques in herpesvirus research.

CRISPR is a gene editing technique with incredible potential. But the traditional CRISPR-Cas9 approach involves cutting the double helix of DNA in cells, which can have many unintended and dangerous ...

Researchers have introduced 'prime assembly,' a genome editing approach that allows insertion of large DNA segments, enabling entire gene replacements. The method avoids harmful double-strand breaks ...

PHILADELPHIA— A new approach to the genetic engineering of cells promises significant improvements in speed, efficiency, and reduction in cellular toxicity compared to current methods. The approach ...

A novel genome editing technique, NICER, is based on the creation of multiple nicks in single DNA strands by nickase. The method can correct heterozygous mutations using two mechanisms: multiple nicks ...

Genes contain the information necessary for coding the proteins in biological cells. Editing genes is the cornerstone of research into the interrogation of the genetic basis of metabolic and ...

Genetic editing holds promise to treat incurable diseases, but the most popular method — CRISPR — sometimes does more harm than good. A new study from University of California San Diego and Yale ...

A powerful new approach for the precise, flexible modification of a broad class of chemical compounds called bicyclic aza-arenes—which are commonly used to build drug molecules—has been developed. The ...