Plasmid DNA (pDNA) is a fundamental starting material for therapeutic development, including for viral vectors, mRNA therapies, and DNA vaccines. Researchers use capture methods such as anion exchange ...

IN several laboratories, where whole lipid extracts are chromatographed on silicic acid in chloroform-methanol, experience has suggested the need for continuous concave gradient elution. Devices are ...

A new, robust method for protein elution from ceramic hydroxyapatite. Hydroxyapatite is used for the fractionation and purification of a wide variety of biological molecules. At commercial scale, the ...

Epitope tagging is a technique that employs genetic engineering to fuse a known epitope, called an affinity tag, to either the C or N terminus of a recombinant protein to facilitate affinity ...

Several chromatographic resins are available for downstream purification. Monoclonal antibodies (mAbs) are a successful class of therapeutic products used increasingly in the past 15-20 years, but the ...