Frontotemporal dementia or Frontotemporal Lobar Degeneration (FTLD) disease, as it is now known, has been making news recently due in large part to actor Bruce Willis’ diagnosis. At Benchmark at Rye, ...
November 30, 2011 — Positron emission tomography (PET) using the amyloid tracer Pittsburgh compound B (PiB-PET) can discriminate Alzheimer's disease (AD) from frontotemporal lobar degeneration (FTLD) ...
Just days after the first report of a highly eccentric translation mechanism in the major genetic forms of ALS and FTLD comes a second paper showing the same phenomenon. In the February 12 Neuron, ...
A variant of the TMEM106B gene, originally discovered in people with frontotemporal lobar degeneration with TDP-43 pathology, influences the TDP-43 protein in other neurodegenerative diseases too, ...
The mutated and aggregated protein FUS is implicated in two neurodegenerative diseases: amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD). Using a newly developed fruit ...
The protein β-arrestin-2 increases the accumulation of neurotoxic tau tangles, a cause several forms of dementia, by interfering with removal of excess tau from the brain, a new study by the ...
Researchers have identified patterns of neuropsychiatric symptoms that may reveal when Alzheimer’s disease occurs alongside ...
Genetic diagnosis of frontotemporal lobar degeneration has become challenging since the identification of a number of autosomal dominantly inherited causative mutations. As highlighted in a new paper, ...
Movement disorder ALS and cognitive disorder FTLD show strong molecular overlaps, new study shows. Single-cell gene expression patterns in the brain’s motor and frontal cortex, and evidence from ...
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