Scientists have found an essential factor from the extracellular matrix that regulates functionality of the breast tissue for instance during pregnancy. Scientists at the University of Helsinki have ...

Macrophages are central to mechanobiology research: their physical characteristics-stiffness, adhesion, and ECM (extracellular matrix) sensing-are inextricably linked to their phenotypic polarization ...

Christopher H. Contag explores how tissue regeneration involves organized interactions beyond just cell replacement, highlighting two emerging technologies ...

The challenges of connecting molecular changes to tissue structure and highlights the potential of multifractal frameworks to quantify complex biological patterns ...

A joint research team develops robust and stretchable extracellular matrix (ECM) membrane reinforced by nanofiber scaffolds. Animal models are widely used for evaluating a drug in its development ...

Scientists have engineered a lab-on-a-chip system capable of applying precisely controlled mechanical forces to biological materials that mimic the extracellular matrix.

For in vitro cellular assays, the extracellular matrix—the material between cells—often is overlooked, but changes within this microenvironment affect cells’ proliferation and differentiation and, ...

Amyotrophic lateral sclerosis and frontotemporal dementia are heterogeneous diseases that are difficult to fully model in mice. One of the more common forms is caused by hexanucleotide repeat ...

Scientists at the University of Helsinki have found an essential factor from the extracellular matrix that regulates functionality of the breast tissue for instance during pregnancy. Extracellular ...

Animal models are widely used for evaluating a drug in its development stage, but tighter regulations on animal testing and limitations resulting from differences among species are driving the demand ...