Much of the phenotypic variation that is observed within and between species is the result of differences in gene regulation: specifically when, where and how much the genes are expressed. Given the ...

An understanding of the origin and dynamics of heritable genetic variation within classical animal breeding programs is needed to provide the context for understanding the contributions and concerns ...

Researchers have determined whether a specific chemical modification of a protein that packages the genome called a histone affects gene activity and cell proliferation. Researchers have determined ...

Discover how CRISPR genome editing is revolutionizing medicine. Learn the science of Cas9, current clinical trials, and the ...

Study shows GM gene-edited rice is not “substantially equivalent” to the parental non-edited rice. Report: Claire Robinson and Prof Michael Antoniou ...

Mice and newts were applied to the one-step Cre-loxP organism creation technology by TAx9. In this study, the researchers succeeded in synthesizing a Cre-loxP integrated vector by placing a short DNA ...

DNA can also be demethylated, either through passive or active processes. Passive DNA demethylation occurs when the methylation pattern is not replenished during DNA replication and gradually ...

Researchers demonstrated how Mycobacterium tuberculosis modifies its DNA and regulates both replication and gene activity through a reversible process known as ADP-ribosylation. This is the first time ...

A recent study led to the development of a powerful epigenetic editing technology. The system unlocks the ability to precisely program chromatin modifications at any specific position in the genome, ...

Researchers discover a protein that connects GLP-1 drugs to long-term, broad genomic responses that can promote pancreatic ...

Visit NAP.edu/10766 to get more information about this book, to buy it in print, or to download it as a free PDF. With a growing human population and rising living standards, demand for animal-derived ...