Cross-species research shows that RNA splicing patterns, not just gene activity, track maximum lifespan in mammals, revealing ...

Gene regulation is the process by which cells control the expression of their genes, determining when, where, and to what extent each gene is expressed. It is a fundamental mechanism that allows cells ...

An innovative CRISPR-Cas12f-based activator system may hold significant potential in the future of gene therapy and biological research, suggest researchers of a new study. The study highlights the ...

Researchers at Pohang University of Science and Technology (POSTECH) have built a platform that steers cell behavior using ...

A new software package called CREsted, published in Nature Methods, gives researchers an end-to-end workflow for modeling and ...

Epigenetics is the study of various heritable alterations that control gene expression without changing the DNA sequence. 1 The name epigenetics comes from the Greek prefix “epi”, which means on top ...

A figure from the paper illustates a key finding of "compromised compartmentalization": chromatin that was locking genes down in health became more open in Alzheimer's, while chromatin that was open ...

Long non-coding RNAs (lncRNA) are a type of RNA molecule that do not carry instructions to make proteins. Instead, they influence how other genes are expressed. There are tens of thousands of lncRNAs ...

Targeting organ‑specific gene “switches” can reverse key markers of liver aging in mice, suggesting aging might be slowed one ...