After so many years of learning how microbes work, researchers are now digitally recreating their inner workings to tackle challenges ranging from climate change to space colonization. In my work as a ...

Metabolic and regulatory networks may be expanded by coupling high-throughput phenotyping and gene expression data with the predictions of a computational model. (Reprinted with permission, Nature, ...

Scientists have developed a genome-scale metabolic model or 'subway map' of key metabolic activities of the bacterium that causes Lyme disease. Using this map, they have successfully identified two ...

The integrated systems biology workflow for cancer subtyping and early diagnosis. The pipeline combines multi-omic data with metabolic modeling to generate patient-specific flux distributions, which ...

A new approach to treating inflammatory diseases through personalised probiotic therapies -- also known as precision medicine -- has been proposed by researchers. A new approach to treating ...