Immunoglobulins are central to shaping immune responses and are critical tools for probing biological mechanisms in biomedical research. However, selecting an inappropriate antibody isotype can lead ...

The lower hinge of immunoglobulin G (IgG), an overlooked part of the antibody, acts as a structural and functional control hub, according to a study by researchers at Science Tokyo. Deleting a single ...

As scientists uncover how age-altered antibodies ignite inflammation and tissue decline, a new era of immune-based anti-aging therapies is beginning to emerge. Aging affects B cells and induces ...

AI‑designed intracellular antibody fragments can stay stable inside cells and bind misfolded proteins, opening new treatment ...