Cellular homeostasis requires transcriptional outputs to be coordinated, and many events post transcription initiation can dictate the levels and functions of mature transcripts. To systematically ...

Gene expression is a highly regulated process, which involves several steps. These include transcription of DNA instructions into RNA, removal of non-coding segments from the RNA message, and its ...

A study by Duke-NUS Medical School has found that members of the multiprotein 'Integrator complex', known for its role in gene regulation, are crucial for healthy brain development in fruit flies. The ...

Fruit fly studies reveal proteins that promote healthy nervous system development by preventing the reversal of nerve cell differentiation. A study by Duke-NUS Medical School has found that members of ...

The study of the genome once seemed like a straightforward process: a specific short sequence of three nucleotide bases in DNA was a sign that indicated where a protein's sequence began. This ...

SINGAPORE, 24 April 2019 - A study by Duke-NUS Medical School has found that members of the multiprotein 'Integrator complex', known for its role in gene regulation, are crucial for healthy brain ...