Hyperthermic intraperitoneal chemotherapy (HIPEC) provides an important treatment option that can improve survival for some patients with advanced peritoneal cancer. Managing this disease — and ...
Drug delivery systems can alter drug clearance from the peritoneal cavity and drug toxicity profiles. For example, IP injection of cisplatin-loaded polymeric microspheres (100–200 µm, which releases ...
Dedrick and colleagues presented the distributed model to describe drug penetration in the peritoneum, which is perfused by capillaries. [27–30] This model assumes drug transfer across ...
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