THE liver acts as a selective barrier between the gastrointestinal tract and the systemic circulation, metabolizing, detoxifying and elaborating for further physiologic disposition various substances ...

Drugs are metabolized in the liver using several enzyme-catalyzed processes. These enzymes are collectively referred to as the hepatic microsomal enzyme system, and they are usually present in the ...

REFLECTION on the functional significance of the valves in the veins and in the heart led Colombo and Cesalpino to postulate a circulatory system in place of the long-accepted tidal flow of blood from ...

Liver disease not only affects the digestion process, metabolism, and detoxification but can also trigger serious ...

In a breakthrough that brings bioengineered organs one step closer to reality, scientists have created lab-grown liver tissue capable of forming its own blood vessels. A team from Cincinnati ...

In a clinical guideline issued by the American College of Gastroenterology and published in the March issue of the American Journal of Gastroenterology, recommendations are presented for the diagnosis ...

Learn how bioavailability can be determined in vitro using human cells Discover how gut-liver MPS can be used to evaluate a key ADME parameter Discuss the application of mathematical modeling to ...

The most common types of primary liver cancer are hepatocellular carcinoma (also known as hepatoma) and cholangiocarcinoma. However, cancer in the liver has often metastasised from other sites such as ...