Local anesthetics have transformed clinical practice by enabling a broad range of minor and major procedures with minimal discomfort. Although adverse reactions are frequently reported, genuine ...

The localized loss of sensation with resultant reduction in pain stimuli is the end result of local anesthesia. This mode of anesthesia is considered to be safer than general anesthesia, because it ...

A new study has uncovered how the commonly used local anesthetic drug, lidocaine, activates bitter taste receptors to exert an anti-cancer effect in head and neck cancers. Given its low cost and ready ...

A new study published in the Feb. 2012 issue of Anesthesiology found that the type of lipid emulsion used to reverse toxicity of local anesthetics may change the effectiveness of the reversal, ...

All current local anesthetics block sensory signals—pain—but they also interrupt motor signals, which can be problematic. For example, too much epidural anesthesia can prevent mothers in labor from ...

Does providing postoperative local anesthetic in addition to intravenous analgesics improve comfort in children undergoing dental surgery under general anesthesia? Research presented on March 24 at ...

Between two types of local anesthetics, there are 132 in short supply and 13 available, according to the American Society of Health-System Pharmacists. Twenty bupivacaine injections from Pfizer are ...

Deaths from lidocaine poisonings more than doubled since 2010, calls to poison control centers suggested. Calls about local anesthetic poisonings decreased by 23%, mainly due to fewer non-lidocaine ...

All current local anesthetics block sensory signals — pain — but they also interrupt motor signals, which can be problematic. For example, too much epidural anesthesia can prevent mothers in labor ...