Epigenetics, the modification of chromosomes without altering DNA sequences, serves as a crucial regulatory mechanism for gene expression. Among the various epigenetic marks, N6-methyladenosine (m6A) ...

Emerging research highlights the transformative potential of m6A RNA modification in the diagnosis and treatment of cardiovascular diseases (CVDs). As the most abundant internal modification of ...

Image Caption: The molecular mechanism of m6A methylation. Genes & Diseases publishes rigorously peer-reviewed and high quality original articles and authoritative reviews that focus on the molecular ...

Duke researchers published a breakthrough in understanding m6A through the development of a genetically encoded sensor for the most abundant internal mRNA modification. These mRNA modifications are ...

Effect and mechanism of STF-31 combined with cisplatin in overcoming platinum resistance in ovarian cancer.

Researchers at the Ohio State University report they have settled a matter of scientific debate. In a new study, the researchers discovered a chemical modification in the HIV-1 RNA genome that is now ...

A chemical modification in the HIV-1 RNA genome whose function has been a matter of scientific debate is now confirmed to be key to the virus's ability to survive and thrive after infecting host cells ...