The landscape of novel monoclonal antibody (mAb) therapeutic formats has expanded significantly in recent years, introducing new challenges in the purification process. Traditional full-length IgG ...

Matt Taylor is a senior process development associate at KBI Biopharma, where he focuses on the design, optimization, and scale-up of purification processes for biopharmaceutical manufacturing. Matt ...

Catalent Pharma Solutions and 3M Purification Inc., recently investigated a novel purification approach that significantly increased the performance of the mAb purification process by enhancing the ...

Next-generation monoclonal antibodies (mAbs), including bispecifics and multimerized formats, present increasingly complex purification challenges. Unique structural features and elevated impurity ...

At-line process monitoring (ALPM) is a major application of ultra-high performance size-exclusion chromatography (UHP-SEC). ALPM of biological drugs helps to reduce the time and effort associated with ...

Raman spectroscopy is a non-destructive analysis technique that is outstanding for measuring the frequencies of chemical bond vibrations. As these occur at particular energies relying on the exact ...

The acquisition will add Belgium-based chromatography operations and a team of over 50 employees to Merck.

Antibodies are characterized by two functionally important regions, the Fab (two of which are present in a single antibody molecule) and the Fc, the former dictating target specificity and the latter ...

Development of robust purification processes requires significant time and resources. In addition, steadily increasing demands from regulatory authorities for better understanding and control of ...

AGC Biologics, a leading global Biopharmaceutical Contract Development and Manufacturing Organization (CDMO), today announced a new research paper from its global research and development Center (R&D ...