The team first constructed cell-specific metabolic network models by integrating proteomic data obtained from two different types of drug-resistant MCF7 breast cancer cell lines: one resistant to ...

Metabolic networks constitute the complex web of biochemical reactions that sustain cellular life, integrating enzymes, substrates, and regulatory elements. Systems biology provides the framework to ...

Two papers published today in the journal Nature describe a significant advance in understanding the complex functions of the metabolic network. The research is from the lab of Marian Walhout, PhD, ...

Two new papers describe a significant advance in understanding the complex functions of the metabolic network. Two papers published today in the journal Nature describe a significant advance in ...

Mitochondrial dysfunction manifests as structural damage (swelling, cristae rupture, increased volume/decreased numerical density), energy metabolism abnormalities (reduced COX and Complex I-III ...