Cell–cell interactions in the tumour microenvironment are often mediated by ligand proteins secreted by one cell that are recognized by specific receptors presenting on neighbouring cells. This ...
Characterization of the tumor transcriptomic differences by smoking history in locally advanced or metastatic urothelial carcinoma (UC). Utility of ctDNA in predicting outcome and pathological ...
Effect of Hyperthermic Intraperitoneal Chemotherapy on Cytoreductive Surgery in Gastric Cancer With Synchronous Peritoneal Metastases: The Phase III GASTRIPEC-I Trial We analyzed 2,162 LN+ patients, ...
A new research paper was published in Oncotarget's Volume 15 on July 12, 2024, entitled, "INT-1B3, an LNP formulated miR-193a-3p mimic, promotes anti-tumor immunity by enhancing T cell mediated immune ...
Figure 7: Proposed mode of action of INT-1B3/1B3. INT-1B3/1B3 induces apoptosis and cell death leading to expression of DAMPs, e.g., expression of calreticulin, reduced expression of CD39 and CD73 and ...
A schematic overview illustrating how the immune microenvironment is involved in diseases across various systems, including respiratory, cardiovascular, and digestive systems. Targeting cellular ...
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