RNA interference (RNAi) is a conserved post-transcriptional gene regulatory pathway whereby short non-coding RNAs guide silencing complexes to complementary messenger RNAs, resulting in translational ...
Osteogenic differentiation of mesenchymal stem cells (MSCs) is orchestrated by a sophisticated network of non‐coding RNAs (ncRNAs), including microRNAs (miRNAs), long non‐coding RNAs (lncRNAs) and ...
What keeps our cells the right size? Scientists have long puzzled over this fundamental question, since cells that are too large or too small are linked to many diseases. Until now, the genetic basis ...
Long non-coding RNAs (lncRNA) are a type of RNA molecule that do not carry instructions to make proteins. Instead, they influence how other genes are expressed. There are tens of thousands of lncRNAs ...
Northwestern Medicine scientists have discovered that a specific long non-coding RNA activates oncogenic signaling pathways in prostate cancer cells and drives tumor progression, underscoring its ...
In back-to-back studies published in Nature, researchers from Purdue University and Columbia University report a naturally evolved gene-editing system that can activate genes, offering an advantage ...
A long‑overlooked stretch of the human genome appears to play a distinct role in shaping the social and stereotypic repetitive behaviours that define Autism Spectrum Disorder (ASD), without affecting ...
A newly published review article brings attention to the expanding role of RBM15, a critical regulator of RNA m6A methylation, in the development and progression of a wide range of diseases, including ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results