A light brush of fabric against skin should not cause agony. But for the roughly 51 million American adults living with ...

Deep within the brain, scientists have uncovered a hidden “switch” that may decide whether pain fades away—or lingers for ...

Most people with chronic back pain naturally think their pain is caused by injuries or other problems in the body such as arthritis or bulging disks. But our research team has found that thinking ...

Scientists have recreated the brain circuit responsible for transmitting feelings of pain for the first time. The breakthrough, made by a team at Stanford University in the US, could help with ...

Scientists have re-created a pain pathway in the brain by growing four key clusters of human nerve cells in a dish. This laboratory model could be used to help explain certain pain syndromes, and ...

Stanford Medicine investigators have replicated, in a lab dish, one of the most prominent human nervous pathways for sensing pain. This nerve circuit transmits sensations from the body’s skin to the ...

Three floors below Dmitriy Sheyn’s lab at Cedars-Sinai Medical Center, doctors remove degenerated intervertebral discs from patients with severe back pain. Instead of tossing the old discs, however, ...

In a new study, researchers from North Carolina State University show that itch sensations in the face are perceived differently from those in the body due to differences in signaling between ...

Chronic pain is no joke. It can upend your life, steal away your ability to live in the moment and force you to find gumption within yourself you didn’t know existed. It’s something that an estimated ...

Estrogen may cause certain colon cells, shown in green in this microscope image, to release a hormone called peptide YY. This, in turn, causes a different type of colon cell, colored magenta, to pump ...