The origin of sensory ganglia in the developing peripheral nervous system can be traced to two transient embryonic cell populations: the neural crest and ectodermal placodes 1. Both cell types ...

The entire inner ear and the neurons that innervate it derive from a simple piece of embryonic ectoderm next to the hindbrain called the otic placode. This ectoderm thickens, invaginates and folds up ...

Hairs in mammals, feathers in birds and scales in reptiles have evolved from their common reptilian ancestor. Mammalian hairs and avian feathers develop from a similar primordial structure called a ...

A mechanism that cells use to group together and move around the body -- called 'chase and run' -- has been described for the first time by scientists. A mechanism that cells use to group together and ...

Based on conserved developmental principles, we have developed a simple but highly efficient platform to convert human PSCs into neural tissue. We have shown that dual-SMAD inhibition via small ...