Staff at Salt Lake City-based techbio company Recursion recently heard from Jenny and Tim Jones about their challenging ...

Familial adenomatous polyposis is caused by abnormalities in the APC gene. The Food and Drug Administration (FDA) has granted Fast Track designation to REC-4881 for the treatment of familial ...

Please provide your email address to receive an email when new articles are posted on . For patients with familial adenomatous polyposis, incidence of disease progression was not significantly lower ...

ST316 interfered with β-catenin immune-exclusion allowing for stronger cytotoxic T-cell activity. The Food and Drug Administration (FDA) has granted Orphan Drug designation to ST316 for the treatment ...

Juvenile polyposis syndrome (JPS) refers to a condition in which there are multiple benign polyps in the colon, or large intestine. Polyps are outgrowths occurring on the inside of a hollow organ. The ...

Role of independent data-monitoring committees in randomized clinical trials sponsored by the National Cancer Institute. BTP patients encompass a heterogeneous group that can be classified into two ...

Germ-line mutations in the base-excision–repair gene MYH have been associated with recessive inheritance of multiple colorectal adenomas. Tumors from affected persons displayed excess somatic ...

Background A 64-year-old woman presented to the emergency room with a 3-month history of intermittent abdominal cramps, accompanied by nausea, vomiting, anorexia, and decreased bowel movements ...

Background A 22-year-old woman was referred to a genomic medicine clinic for evaluation of suspected Prader–Willi syndrome (PWS) after normal DNA methylation studies on chromosome 15 were obtained.

Juvenile polyposis syndrome, also known as familial juvenile polyposis, is a hereditary genetic syndrome. It is usually transmitted in an autosomal dominant fashion, but may be due to a new mutation ...