In recent years, fluorescence quenching microscopy (FQM) 1-3 has emerged as a viable technique that allows for the swift, cost-effective, and accurate imaging of two-dimensional (2D) materials like ...

FLIM principles. Schematic overview of fluorescence lifetime data acquisition and analysis in time−domain (td) and frequency−domain (fd) modes. In tdFLIM, photon arrival times are recorded after each ...

The core mechanism involves labeling a target molecule, substrate, or probe with a fluorophore. Upon excitation, the fluorophore emits a signal that is proportional to the presence or activity of the ...

Biologists are very interested in how proteins, lipids and other compounds are organized and interact in systems. Very few organizational details can be gained by using standard transmission-based ...

A hybrid microscope allows scientists to simultaneously image the full 3D orientation and position of an ensemble of molecules, such as labeled proteins inside cells. The microscope combines polarized ...

Stanford researchers have combined two microscopy techniques to create a one-of-a-kind instrument that can show cell structures interacting in real time at an unprecedented 120-nanometer ...

A new two-photon fluorescence microscope developed at UC Davis can capture high-speed images of neural activity at cellular resolution thanks to a new adaptive sampling scheme and line illumination.