Scientists demonstrated that glial fibrillary acidic protein (GFAP) promotes mitochondrial fission rather than blocking fusion. The genetic disorder Alexander disease is caused by mutations in the ...

Alzheimer's disease affects an estimated 7.2 million Americans age 65 and older, according to the Alzheimer's Association. Current tests often measure the levels of two proteins-amyloid beta (Aβ) and ...

Proteoforms, the diverse molecular variants of proteins, are key to understanding cellular functions, disease mechanisms, and ...

A team of researchers has developed a method that could transform the field of protein engineering. The new approach, called AI-informed Constraints for protein Engineering (AiCE), enables rapid and ...

Intrinsically disordered proteins lack a fixed structure, which is why they have been considered "undruggable" targets for ...

Protein engineering is a powerful biotechnological process that focuses on creating new enzymes or proteins and improving the functions of existing ones by manipulating their natural macromolecular ...

The “ChatGPT moment” for biology proceeds to unfold as protein language models, or machine learning tools trained on large databases of protein sequences, work to decode the language of life with the ...

Scientists have for the first time looked deep into the protein structure that may determine our vision - and discovered that it is much more dynamic than previously thought. RBP3 not only changes its ...

AI protein function prediction uses machine learning models trained on sequence and structural data to infer protein roles at ...