New research reveals how the RapA enzyme protects against R-loop cytotoxicity in E. coli. Genetically speaking, it's a bacterium's worst-case scenario: during transcription, newly minted RNA sticks to ...
A mechanism by which knockouts of maternal mRNA clearing factors lead to zygotic arrest in mice. Abnormal accumulation of maternal mRNAs in mouse zygotes leads to transcriptional leakage before the ...
Genetically speaking, it's a bacterium's worst-case scenario: During transcription, newly minted RNA sticks to its DNA template, forming a 3-stranded structure known as an R-loop. While these ...
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