Researchers have successfully demonstrated how astroglia—cells that support the functioning of the brain—can be reprogrammed into cells resembling interneurons. The research, published in Science ...

A newly discovered molecule, OLE, restored the brain's immune cells to a more protective state in Alzheimer's disease models.

A mechanism underlying neutrophil reprogramming in brain cancers has been uncovered, illuminating potential therapeutic targets to stop their pro-cancer effect. Tumor-infiltrating neutrophils are ...

The lab of Filippo Veglia, Ph.D., at The Wistar Institute has discovered a previously unknown mechanism for how aggressive brain cancers reprogram immune system cells from fighting cancer to enabling ...

When a neuron ages, it loses synaptic connections with other neurons, it is less able to transmit nerve impulses, and its metabolism is also altered. This process of neuronal ageing — inevitable with ...

Promising mouse studies and billions of dollars in funding are stoking excitement. But we’ve been here before.

A newly discovered molecule, OLE, restored the brain’s immune cells to a more protective state in Alzheimer’s disease models. The treatment reduced the accumulation of toxic plaques and improved ...