Clear cell renal cell carcinoma (ccRCC) is a common type of cancer in the urinary system. Currently, the first-line treatments for advanced or metastatic ccRCC are tyrosine kinase inhibitors (TKIs); ...
The DNp73 proteins act as trans-repressors of p53 and p73-dependent transcription and exert both anti-apoptotic activity and pro-proliferative activity. DNp73s are frequently up-regulated in a variety ...
The mechanism(s) by which Zika virus (ZIKV) antagonizes IFN signaling is unknown. This visual abstract depicts the findings of Grant et al., who report that the nonstructural NS5 protein of ZIKV binds ...
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