Sequence analysis is a cornerstone of modern bioinformatics, encompassing the computational exploration of biological sequences—be they DNA, RNA or proteins—to reveal insights into structure, function ...

Dayhoff Health and AMD publish a joint white paper documenting up to 330× faster microbiome processing, 13–22× faster ...

This illustration demonstrates how metapipeline-DNA processes raw genome sequencing data. It begins by aligning the sequence of DNA base pairs to a reference genome. Then produces sets of detected ...

Long-read sequencing technologies analyze long, continuous stretches of DNA. These methods have the potential to improve researchers' ability to detect complex genetic alterations in cancer genomes.

This study demonstrates that NGS-MSI is noninferior to IHC-MMR and can identify MSI-H tumors that IHC-MMR is unable to detect and conversely IHC-MMR can identify MMRd tumors that NGS-MSI misses. This ...

High background noise in RNA samples can impact read accuracy and increase sequencing costs. Optimizing sample quality enables better microRNA mapping and more reliable insights in transcriptomics and ...

Stanford develops protein-to-DNA method enabling high-throughput protein sequencing Technique detects up to 1,000 times more ...

DNA methylation is a highly studied epigenetic modification that is involved in regulating genome function and plays fundamental roles in development and disease. 1 It is linked to a broad range of ...

The discipline of bioinformatics integrates biology and computer science to improve our understanding of complex biological systems. Bioinformatic analysis describes the processing of biological data ...

Researchers at EMBL’s European Bioinformatics Institute (EMBL-EBI) have developed a new machine learning method called SAVANA that significantly reduces sequencing errors for cancer genomes. Long-read ...