BUFFALO, NY- January 13, 2023 – A new research paper was published in Genes & Cancer on December 14, 2022, entitled, “Slit2 signaling stimulates Ewing sarcoma growth.” Ewing sarcoma is a cancer of ...

The neuronal repellent SLIT2 is repressed in a number of cancer types primarily through promoter hypermethylation. SLIT2, however, has not been studied in prostate cancer. Through genome-wide location ...

Local environmental cues are indispensable for axonal growth and guidance during brain circuit formation. Here, we combine genetic and pharmacological tools, as well as systems neuroanatomy in human ...

A new research paper was published in Genes & Cancer on December 14, 2022, entitled, "Slit2 signaling stimulates Ewing sarcoma growth." Ewing sarcoma is a cancer of bone and soft tissue in children ...

Vasoproliferative ocular diseases are responsible for sight loss in millions of people in the industrialised countries. Many patients do not currently respond to the treatment offered, which targets a ...

Blocking another protein, Slit2, prevents the pathological blood vessel development that causes blindness diseases, a team of Inserm researchers has demonstrated in an animal model. Vasoproliferative ...

Metastasis is responsible for the great majority of deaths in cancer patients. There are three primary ways tumors metastasize to other organs: through the circulatory system, through the lymphatic ...

About 10% of acute hepatitis cases and 50% of acute liver failure are caused by drug induction, where treatment remains largely limited. The SLIT/ROBO signaling axis is composed of the secretory SLIT ...

Mutations in the gene that codes for SLIT2, a protein expressed in fetal cells in placentas and involved in directing the growth of the fetal nervous system, may contribute to premature births, ...