Together, these findings suggest that ferulic acid can act as a natural regulator of intestinal motility. By reducing excessive smooth muscle activity, the compound could potentially help calm ...

The contractile responses of esophageal smooth muscle (SM) induced by platelet-activating factor (PAF) involve the activation of L-type voltage-dependent calcium channels (L-type VDCCs), ...

IT is generally believed that the process which initiates contraction in striated muscle is the depolarization of the excitable membrane of the muscle fibre, although the mechanism by which membrane ...

A research group led by Dr. Keisuke Obara, Dr. Kento Yoshioka, and Professor Yoshio Tanaka from the Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Toho University, has ...

Ferulic acid suppresses ileal smooth muscle contraction by inhibiting calcium ion influx through voltage-dependent calcium channels. This action may help prevent or treat excessive intestinal motility ...

The treatments for bronchospam have not changed in the past 50 years, Panettieri said, since they work for most - but not all people. The microdevice allowed us to drill down into how single cells ...

Panel A shows the microscopic myoarchitecture of the circular and longitudinal muscle layers of the lower esophageal sphincter and stomach. The circular muscle fibers of the esophagus cross each other ...

Isometric exercises are exercises that involve the contraction of muscles without any movement in the surrounding joints. Most muscle strengthening exercises involve moving the joints, using the ...