Spatial ribonucleic acid (RNA) transcriptomics measures gene expression while preserving each molecule’s coordinates in intact tissue, tying transcripts to histology and local microenvironments.

A wave of spatial transcriptomics studies has produced gene-expression atlases that span entire organs and whole organisms, ...

A team of researchers has constructed the most detailed single-cell map of the adult human prostate to date, cataloging more than 253,000 individual cells and identifying previously hidden ...

A new spatial transcriptomic approach captures the regulation of splicing and polyadenylation sites during pubescent brain development at near-single-cell resolution. An international collaboration, ...

Fei Chen and Chenlei Hu at the Broad Institute of MIT and Harvard have developed a new imaging-free spatial transcriptomics technology that tracks the diffusion of DNA barcodes between beads in an ...

Challenges and Prospects. Challenges and prospects faced by spatial transcriptomics itself and its application to the musculoskeletal system. AI Artificial intelligence, FFPE Formalin fixed and ...

Foundation models (FMs), which are deep learning models pretrained on large-scale data and applied to diverse downstream ...

Integration of Takara Bio USA’s Trekker® reagent kit with Illumina’s Single Cell 3′ RNA Prep assay delivers high-density, high-sensitivity spatial data with true single-cell resolution Takara Bio USA, ...

Left: Imaging of lamin A/C structures in a physically expanded nucleus from an individual with progeria. Right: Same, but with 3D genomic reads overlaid in their original spatial locations, colored by ...

Essentially all cells in an organism's body have the same genetic blueprint, or genome, but the set of genes that are actively expressed at any given time in a cell determines what type of cell it ...