Mitotic segregation of chromosomes depends on correct assembly of the bipolar spindle and mitosis is delayed by the spindle assembly checkpoint (SAC). In the July 19 Nature, Gachet et al., at the ...
Accurate chromosome segregation and cell division are central to maintaining genomic integrity and ensuring proper development and tissue homeostasis. These processes rely on a complex network of ...
Recent evidence has suggested threonine tyrosine kinase (TTK) as a crucial element of the mitotic checkpoint for the correct functioning of spindle assembly checkpoint (SAC), making it a potential ...
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